| Sham Stakes | Jan 2, 2021 | Santa Anita | 3YO R D | 3 | | 8.0 | Main | 3 |
| Tropical Turf Stakes | Jan 9, 2021 | Gulfstream Park | 3UP R T | 3U | | 8.0 | T | 3 |
| La Canada Stakes | Jan 9, 2021 | Santa Anita | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| Las Cienegas Stakes | Jan 9, 2021 | Santa Anita | 3UP T SPR | 3U | f | 6.0 | T | 3 |
| Louisiana Stakes | Jan 16, 2021 | Fair Grounds | 3UP R D | 3U | | 8.5 | Main | 3 |
| Lecomte Stakes | Jan 16, 2021 | Fair Grounds | 3YO R D | 3 | | 8.5 | Main | 3 |
| Astra Stakes | Jan 17, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 12.0 | T | 3 |
| Megahertz Stakes | Jan 18, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 8.0 | T | 3 |
| La Prevoyante Stakes | Jan 23, 2021 | Gulfstream Park | 3UP F/M RT | 3U | f | 12.0 | T | 3 |
| Marshuas River Stakes | Jan 23, 2021 | Gulfstream Park | 3UP F/M RT | 3U | f | 8.0 | T | 3 |
| Fred W Hooper Stakes | Jan 23, 2021 | Gulfstream Park | 3UP R D | 3U | | 8.0 | Main | 3 |
| W L Mcknight Stakes | Jan 23, 2021 | Gulfstream Park | 3UP R T | 3U | | 12.0 | T | 3 |
| Palos Verdes Stakes | Jan 23, 2021 | Santa Anita | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Sweetest Chant Stakes | Jan 30, 2021 | Gulfstream Park | 3YO F R T | 3 | f | 8.0 | T | 3 |
| Forward Gal Stakes | Jan 30, 2021 | Gulfstream Park | 3YO F SPR | 3 | f | 7.0 | Main | 3 |
| Holy Bull Stakes | Jan 30, 2021 | Gulfstream Park | 3YO R D | 3 | | 8.5 | Main | 3 |
| Kittens Joy Stakes | Jan 30, 2021 | Gulfstream Park | 3YO R T | 3 | | 8.0 | T | 3 |
| Claiborne Farm Swale Stakes | Jan 30, 2021 | Gulfstream Park | 3YO SPR | 3 | | 7.0 | Main | 3 |
| Robert B Lewis Stakes | Jan 30, 2021 | Santa Anita | 3YO R D | 3 | | 8.5 | Main | 3 |
| Toboggan Stakes | Jan 30, 2021 | Aqueduct | 3UP SPR | 3U | | 7.0 | Main | 3 |
| Houston Ladies Classic Stakes | Jan 31, 2021 | Sam Houston | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| John B Connally Turf Cup Stakes | Jan 31, 2021 | Sam Houston | 3UP R T | 3U | | 12.0 | T | 3 |
| Withers Stakes | Feb 6, 2021 | Aqueduct | 3YO R D | 3 | | 9.0 | Main | 3 |
| Thunder Road Stakes | Feb 6, 2021 | Santa Anita | 3UP R T | 3U | | 8.0 | T | 3 |
| Las Virgenes Stakes | Feb 6, 2021 | Santa Anita | 3YO F R D | 3 | f | 8.0 | Main | 3 |
| Endeavour Stakes | Feb 6, 2021 | Tampa Bay Downs | 3UP F/M RT | 3U | f | 8.5 | T | 3 |
| Tampa Bay Stakes | Feb 6, 2021 | Tampa Bay Downs | 3UP R T | 3U | | 8.5 | T | 3 |
| Sam F Davis Stakes | Feb 6, 2021 | Tampa Bay Downs | 3YO R D | 3 | | 8.5 | Main | 3 |
| Mineshaft Stakes | Feb 13, 2021 | Fair Grounds | 3UP R D | 3U | | 8.5 | Main | 3 |
| Fair Grounds Stakes | Feb 13, 2021 | Fair Grounds | 3UP R T | 3U | | 9.0 | T | 3 |
| Gulfstream Park Sprint Stakes | Feb 13, 2021 | Gulfstream Park | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Gulfstream Park Turf Sprint Stakes | Feb 13, 2021 | Gulfstream Park | 3UP T SPR | 3U | | 5.0 | T | 3 |
| Sweet Life Stakes | Feb 14, 2021 | Santa Anita | 3YO F SPR | 3 | f | 6.0 | T | 3 |
| Royal Delta Stakes | Feb 20, 2021 | Gulfstream Park | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| Runhappy Barbara Fritchie Stakes | Feb 20, 2021 | Laurel Park | 3UP F/M SPR | 3U | f | 7.0 | Main | 3 |
| General George Stakes | Feb 20, 2021 | Laurel Park | 3UP SPR | 3U | | 7.0 | Main | 3 |
| The Very One Stakes | Feb 27, 2021 | Gulfstream Park | 3UP F/M RT | 3U | f | 9.5 | T | 3 |
| Honey Fox Stakes | Feb 27, 2021 | Gulfstream Park | 3UP F/M RT | 3U | f | 8.0 | T | 3 |
| Canadian Turf Stakes | Feb 27, 2021 | Gulfstream Park | 3UP R T | 3U | | 8.5 | T | 3 |
| Herecomesthebride Stakes | Feb 27, 2021 | Gulfstream Park | 3YO F R T | 3 | f | 8.5 | T | 3 |
| Razorback Handicap | Feb 27, 2021 | Oaklawn Park | 3UP R D | 3U | | 8.5 | Main | 3 |
| Southwest Stakes | Feb 27, 2021 | Oaklawn Park | 3YO R D | 3 | | 8.5 | Main | 3 |
| Bayakoa Stakes | Feb 28, 2021 | Oaklawn Park | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| Tom Fool Handicap | Mar 6, 2021 | Aqueduct | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Gotham Stakes | Mar 6, 2021 | Aqueduct | 3YO R D | 3 | | 8.0 | Main | 3 |
| Honeybee Stakes | Mar 6, 2021 | Oaklawn Park | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| 100000 Michelob Ultra Challenger Stakes | Mar 6, 2021 | Tampa Bay Downs | 3UP R D | 3U | | 8.5 | Main | 3 |
| Florida Oaks | Mar 6, 2021 | Tampa Bay Downs | 3YO F R T | 3 | f | 8.5 | T | 3 |
| Santa Ysabel Stakes | Mar 7, 2021 | Santa Anita | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| San Simeon Stakes | Mar 13, 2021 | Santa Anita | 3UP T SPR | 3U | | 6.0 | T | 3 |
| San Luis Rey Stakes | Mar 20, 2021 | Santa Anita | 3UP R T | 3U | | 12.0 | T | 3 |
| Hurricane Bertie Stakes | Mar 20, 2021 | Gulfstream Park | 3UP F/M SPR | 3U | f | 6.5 | Main | 3 |
| Jeff Ruby Steaks | Mar 27, 2021 | Turfway Park | 3YO R D | 3 | | 9.0 | AWT | 3 |
| Orchid Stakes | Mar 27, 2021 | Gulfstream Park | 3UP F/M RT | 3U | f | 11.0 | T | 3 |
| Ghostzapper Stakes | Mar 27, 2021 | Gulfstream Park | 3UP R D | 3U | | 9.0 | Main | 3 |
| Kittens Joy Appleton Stakes | Mar 27, 2021 | Gulfstream Park | 3UP R T | 3U | | 8.0 | T | 3 |
| Santa Ana Stakes | Mar 27, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 10.0 | T | 3 |
| Distaff Handicap | Apr 2, 2021 | Aqueduct | 3UP F/M SPR | 3U | f | 7.0 | Main | 3 |
| Beaumont Stakes | Apr 2, 2021 | Keeneland | 3YO F SPR | 3 | f | 7.0 | Main | 3 |
| Transylvania Stakes | Apr 2, 2021 | Keeneland | 3YO R T | 3 | | 8.0 | T | 3 |
| Excelsior Stakes | Apr 3, 2021 | Aqueduct | 3UP R D | 3U | | 9.0 | Main | 3 |
| Gazelle Stakes | Apr 3, 2021 | Aqueduct | 3YO F R D | 3 | f | 9.0 | Main | 3 |
| Bay Shore Stakes | Apr 3, 2021 | Aqueduct | 3YO SPR | 3 | | 7.0 | Main | 3 |
| Fantasy Stakes | Apr 3, 2021 | Oaklawn Park | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| Providencia Stakes | Apr 3, 2021 | Santa Anita | 3YO F R T | 3 | f | 9.0 | T | 3 |
| Commonwealth Stakes | Apr 3, 2021 | Keeneland | 3UP SPR | 3U | | 7.0 | Main | 3 |
| Las Flores Stakes | Apr 4, 2021 | Santa Anita | 3UP F/M SPR | 3U | f | 6.0 | Main | 3 |
| Count Fleet Sprint Handicap | Apr 10, 2021 | Oaklawn Park | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Ben Ali Stakes | Apr 10, 2021 | Keeneland | 3UP R D | 3U | | 9.0 | Main | 3 |
| Stonestreet Lexington Stakes | Apr 10, 2021 | Keeneland | 3YO R D | 3 | | 8.5 | Main | 3 |
| Baired Doubledogdare Stakes | Apr 16, 2021 | Keeneland | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| Tokyo City Cup Stakes | Apr 18, 2021 | Santa Anita | 3UP R D | 3U | | 12.0 | Main | 3 |
| Kona Gold Stakes | Apr 18, 2021 | Santa Anita | 3UP SPR | 3U | | 6.5 | Main | 3 |
| Bewitch Stakes | Apr 23, 2021 | Keeneland | 3UP F/M RT | 3U | f | 12.0 | T | 3 |
| San Francisco Mile Stakes | Apr 24, 2021 | Golden Gate Fields | 3UP R T | 3U | | 8.0 | T | 3 |
| Senorita Stakes | May 1, 2021 | Santa Anita | 3YO F R T | 3 | f | 8.0 | T | 3 |
| Westchester Stakes | May 1, 2021 | Belmont Park | 3UP R D | 3U | | 8.0 | Main | 3 |
| Santa Barbara Stakes | May 8, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 12.0 | T | 3 |
| Beaugay Stakes | May 8, 2021 | Belmont Park | 3UP F/M RT | 3U | f | 8.5 | T | 3 |
| Vagrancy Handicap | May 8, 2021 | Belmont Park | 3UP F/M SPR | 3U | f | 6.5 | Main | 3 |
| Runhappy Stakes | May 8, 2021 | Belmont Park | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Peter Pan Stakes | May 8, 2021 | Belmont Park | 3YO R D | 3 | | 9.0 | Main | 3 |
| Allaire Dupont Distaff Match Series Stakes | May 14, 2021 | Pimlico | 3UP F/M RD | 3U | f | 9.0 | Main | 3 |
| Pimlico Special Match Series Stakes | May 14, 2021 | Pimlico | 3UP R D | 3U | | 9.5 | Main | 3 |
| Miss Preakness Stakes | May 14, 2021 | Pimlico | 3YO F SPR | 3 | f | 6.0 | Main | 3 |
| Gallorette Stakes | May 15, 2021 | Pimlico | 3UP F/M RT | 3U | f | 8.5 | T | 3 |
| Maryland Sprint Match Series Stakes | May 15, 2021 | Pimlico | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Chick Lang Stakes | May 15, 2021 | Pimlico | 3YO SPR | 3 | | 6.0 | Main | 3 |
| Soaring Softly Stakes | May 15, 2021 | Belmont Park | 3YO F SPR | 3 | f | 7.0 | T | 3 |
| Louisville Stakes | May 15, 2021 | Churchill Downs | 3UP R T | 3U | | 12.0 | T | 3 |
| Lazaro Barrera Stakes | May 15, 2021 | Santa Anita | 3YO SPR | 3 | | 7.0 | Main | 3 |
| Honeymoon Stakes | May 22, 2021 | Santa Anita | 3YO F R T | 3 | f | 9.0 | T | 3 |
| Winning Colors Stakes | May 22, 2021 | Churchill Downs | 3UP F/M SPR | 3U | f | 6.0 | Main | 3 |
| Daytona Stakes | May 29, 2021 | Santa Anita | 3UP T SPR | 3U | | 6.5 | T | 3 |
| Regret Stakes | May 29, 2021 | Churchill Downs | 3YO F R T | 3 | f | 9.0 | T | 3 |
| Matt Winn Stakes | May 29, 2021 | Churchill Downs | 3YO R D | 3 | | 8.5 | Main | 3 |
| Steve Sexton Mile Stakes | May 31, 2021 | Lone Star Park | 3UP R D | 3U | | 8.0 | Main | 3 |
| Intercontinental Stakes | Jun 3, 2021 | Belmont Park | 3UP T SPR | 3U | f | 7.0 | T | 3 |
| Wonder Again Stakes | Jun 3, 2021 | Belmont Park | 3YO F R T | 3 | f | 9.0 | T | 3 |
| Bed O Roses Stakes | Jun 4, 2021 | Belmont Park | 3UP F/M SPR | 3U | f | 7.0 | Main | 3 |
| Monmouth Stakes | Jun 5, 2021 | Monmouth Park | 3UP R T | 3U | | 9.0 | T | 3 |
| Salvator Mile Stakes | Jun 12, 2021 | Monmouth Park | 3UP R D | 3U | | 8.0 | Main | 3 |
| Old Forester Mint Julep Stakes | Jun 12, 2021 | Churchill Downs | 3UP F/M RT | 3U | f | 8.5 | T | 3 |
| Affirmed Stakes | Jun 13, 2021 | Santa Anita | 3YO R D | 3 | | 8.5 | Main | 3 |
| San Juan Capistrano Stakes | Jun 19, 2021 | Santa Anita | 3UP R T | 3U | | 14.0 | T | 3 |
| Wilshire Stakes | Jun 20, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 8.0 | T | 3 |
| American Stakes | Jun 20, 2021 | Santa Anita | 3UP R T | 3U | | 8.0 | T | 3 |
| Poker Stakes | Jun 20, 2021 | Belmont Park | 3UP R T | 3U | | 8.0 | T | 3 |
| Eatontown Stakes | Jun 20, 2021 | Monmouth Park | 3UP F/M RT | 3U | f | 8.5 | T | 3 |
| Chicago Stakes | Jun 26, 2021 | Arlington Park | 3UP F/M SPR | 3U | f | 7.0 | AWT | 3 |
| Bashford Manor Stakes | Jun 26, 2021 | Churchill Downs | 2YO | 2 | | 6.0 | Main | 3 |
| Ohio Derby | Jun 26, 2021 | Thistledown | 3YO R D | 3 | | 9.0 | Main | 3 |
| Iowa Oaks | Jul 2, 2021 | Prairie Meadows | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| Prairie Meadows Cornhusker Handicap | Jul 2, 2021 | Prairie Meadows | 3UP R D | 3U | | 9.0 | Main | 3 |
| Delaware Oaks | Jul 3, 2021 | Delaware Park | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| Kent Stakes | Jul 3, 2021 | Delaware Park | 3YO R T | 3 | | 9.0 | T | 3 |
| Smile Sprint Invitational Stakes | Jul 3, 2021 | Gulfstream Park | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Los Alamitos Derby | Jul 4, 2021 | Los Alamitos | 3YO R D | 3 | | 9.0 | Main | 3 |
| Dwyer Stakes | Jul 5, 2021 | Belmont Park | 3YO R D | 3 | | 8.0 | Main | 3 |
| Dr James Penny Memorial Stakes | Jul 6, 2021 | Parx Racing | 3UP F/M RT | 3U | f | 8.5 | T | 3 |
| Indiana Oaks | Jul 7, 2021 | Indiana Downs | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| Indiana Derby | Jul 7, 2021 | Indiana Downs | 3YO R D | 3 | | 8.5 | Main | 3 |
| Victory Ride Stakes | Jul 10, 2021 | Belmont Park | 3YO F SPR | 3 | f | 6.5 | Main | 3 |
| Robert G Dick Memorial Stakes | Jul 10, 2021 | Delaware Park | 3UP F/M RT | 3U | f | 11.0 | T | 3 |
| Schuylerville Stakes | Jul 15, 2021 | Saratoga | 2YO F | 2 | f | 6.0 | Main | 3 |
| Quick Call Stakes | Jul 15, 2021 | Saratoga | 3YO SPR | 3 | | 5.5 | T | 3 |
| Forbidden Apple Stakes | Jul 16, 2021 | Saratoga | 3UP R T | 3U | | 8.0 | T | 3 |
| Modesty Stakes | Jul 17, 2021 | Arlington Park | 3UP F/M RT | 3U | f | 9.5 | T | 3 |
| Arlington Stakes | Jul 17, 2021 | Arlington Park | 3UP R T | 3U | | 9.5 | T | 3 |
| Sanford Stakes | Jul 17, 2021 | Saratoga | 2YO | 2 | | 6.0 | Main | 3 |
| Molly Pitcher Stakes | Jul 17, 2021 | Monmouth Park | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| Winstar Matchmaker Stakes | Jul 17, 2021 | Monmouth Park | 3UP F/M RT | 3U | f | 9.0 | T | 3 |
| Monmouth Cup Stakes | Jul 17, 2021 | Monmouth Park | 3UP R D | 3U | | 9.0 | Main | 3 |
| Cougar Ii Stakes | Jul 18, 2021 | Del Mar | 3UP R D | 3U | | 12.0 | Main | 3 |
| Lake George Stakes | Jul 23, 2021 | Saratoga | 3YO F R T | 3 | f | 8.0 | T | 3 |
| Caress Stakes | Jul 24, 2021 | Saratoga | 3UP T SPR | 3U | f | 5.5 | T | 3 |
| Baltimorewashington International Turf Cup Stakes | Jul 24, 2021 | Pimlico | 3UP R T | 3U | | 8.0 | T | 3 |
| Shuvee Stakes | Jul 25, 2021 | Saratoga | 3UP F/M RD | 3U | f | 9.0 | Main | 3 |
| Monmouth Oaks | Jul 31, 2021 | Monmouth Park | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| Troy Stakes | Aug 6, 2021 | Saratoga | 3UP T SPR | 3U | | 5.5 | T | 3 |
| West Virginia Governors Stakes | Aug 7, 2021 | Mountaineer Park | 3UP R D | 3U | | 8.5 | Main | 3 |
| West Virginia Derby | Aug 7, 2021 | Mountaineer Park | 3YO R D | 3 | | 9.0 | Main | 3 |
| Saratoga Oaks Invitational Stakes | Aug 8, 2021 | Saratoga | 3YO F R T | 3 | f | 9.5 | T | 3 |
| La Jolla Handicap | Aug 8, 2021 | Del Mar | 3YO R T | 3 | | 8.5 | T | 3 |
| Pucker Up Stakes | Aug 14, 2021 | Arlington Park | 3YO F R T | 3 | f | 9.0 | T | 3 |
| Longacres Mile Handicap | Aug 15, 2021 | Emerland Downs | 3UP R D | 3U | | 8.0 | Main | 3 |
| Rancho Bernardo Handicap | Aug 20, 2021 | Del Mar | 3UP F/M SPR | 3U | f | 6.5 | Main | 3 |
| Philip Handicap Iselin Stakes | Aug 21, 2021 | Monmouth Park | 3UP R D | 3U | | 8.5 | Main | 3 |
| Torrey Pines Stakes | Aug 21, 2021 | Del Mar | 3YO F R D | 3 | f | 8.0 | Main | 3 |
| Green Flash Handicap | Aug 22, 2021 | Del Mar | 3UP T SPR | 3U | | 5.0 | T | 3 |
| Charles Town Oaks | Aug 27, 2021 | Charles Town | 3YO F SPR | 3 | f | 7.0 | Main | 3 |
| Parx Dash Stakes | Aug 31, 2021 | Parx Racing | 3UP T SPR | 3U | | 5.0 | T | 3 |
| New Kent County Virginia Derby | Aug 31, 2021 | Colonial Downs | 3YO R T | 3 | | 9.0 | T | 3 |
| With Anticipation Stakes | Sep 1, 2021 | Saratoga | 2YO | 2 | | 8.5 | T | 3 |
| Saranac Stakes | Sep 4, 2021 | Saratoga | 3YO R T | 3 | | 8.5 | T | 3 |
| Winstar Mint Million Stakes | Sep 6, 2021 | Kentucky Downs | 3UP R T | 3U | | 8.0 | T | 3 |
| Kentucky Downs Ladies Turf Stakes | Sep 11, 2021 | Kentucky Downs | 3UP F/M RT | 3U | f | 8.0 | T | 3 |
| Fanduel Turf Sprint Stakes | Sep 11, 2021 | Kentucky Downs | 3UP T SPR | 3U | | 6.0 | T | 3 |
| Mint Ladies Sprint Stakes | Sep 11, 2021 | Kentucky Downs | 3UP T SPR | 3U | f | 6.5 | T | 3 |
| Iroquois Stakes | Sep 18, 2021 | Churchill Downs | 2YO | 2 | | 8.5 | Main | 3 |
| Pocahontas Stakes | Sep 18, 2021 | Churchill Downs | 2YO F | 2 | f | 8.5 | Main | 3 |
| Locust Grove Stakes | Sep 18, 2021 | Churchill Downs | 3UP F/M RD | 3U | f | 8.5 | Main | 3 |
| Frank J De Francis Memorial Dash Stakes | Sep 18, 2021 | Laurel Park | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Greenwood Cup Stakes | Sep 25, 2021 | Parx Racing | 3UP R D | 3U | | 12.0 | Main | 3 |
| Turf Monster Stakes | Sep 25, 2021 | Parx Racing | 3UP T SPR | 3U | | 5.0 | T | 3 |
| Athenia Stakes | Sep 25, 2021 | Belmont Park | 3UP F/M RT | 3U | f | 9.0 | T | 3 |
| Dogwood Stakes | Sep 25, 2021 | Churchill Downs | 3YO F SPR | 3 | f | 7.0 | Main | 3 |
| Remington Park Oaks | Sep 26, 2021 | Remington Park | 3YO F R D | 3 | f | 8.5 | Main | 3 |
| Oklahoma Derby | Sep 26, 2021 | Remington Park | 3YO R D | 3 | | 9.0 | Main | 3 |
| Belmont Turf Sprint Invitational Stakes | Oct 2, 2021 | Belmont Park | 3UP T SPR | 3U | | 6.0 | T | 3 |
| Lukas Classic Stakes | Oct 2, 2021 | Churchill Downs | 3UP R D | 3U | | 9.0 | Main | 3 |
| Ack Ack Stakes | Oct 2, 2021 | Churchill Downs | 3UP R D | 3U | | 8.0 | Main | 3 |
| Chillingworth Stakes | Oct 3, 2021 | Santa Anita | 3UP F/M SPR | 3U | f | 6.5 | Main | 3 |
| Waya Stakes | Oct 3, 2021 | Belmont Park | 3UP F/M RT | 3U | f | 11.0 | T | 3 |
| Matron Stakes | Oct 9, 2021 | Belmont Park | 2YO F | 2 | f | 6.0 | T | 3 |
| Futurity Stakes | Oct 10, 2021 | Belmont Park | 2YO | 2 | | 6.0 | T | 3 |
| Knickerbocker Stakes | Oct 10, 2021 | Belmont Park | 3UP R T | 3U | | 9.0 | T | 3 |
| Buffalo Trace Franklin County Stakes | Oct 15, 2021 | Keeneland | 3UP T SPR | 3U | f | 5.5 | T | 3 |
| Sycamore Stakes | Oct 22, 2021 | Keeneland | 3UP R T | 3U | | 12.0 | T | 3 |
| Noble Damsel Stakes | Oct 23, 2021 | Belmont Park | 3UP F/M RT | 3U | f | 8.0 | T | 3 |
| Rood And Riddle Dowager Stakes | Oct 24, 2021 | Keeneland | 3UP F/M RT | 3U | f | 12.0 | T | 3 |
| Rubicon Valley View Stakes | Oct 29, 2021 | Keeneland | 3YO F R T | 3 | f | 8.5 | T | 3 |
| Autumn Miss Stakes | Oct 30, 2021 | Santa Anita | 3YO F R T | 3 | f | 8.0 | T | 3 |
| Bold Ruler Handicap | Oct 31, 2021 | Belmont Park | 3UP SPR | 3U | | 7.0 | Main | 3 |
| Turnback The Alarm Handicap | Nov 6, 2021 | Belmont Park | 3UP F/M RD | 3U | f | 9.0 | Main | 3 |
| Nashua Stakes | Nov 7, 2021 | Belmont Park | 2YO | 2 | | 8.0 | Main | 3 |
| Bob Hope Stakes | Nov 14, 2021 | Del Mar | 2YO | 2 | | 7.0 | Main | 3 |
| Native Diver Stakes | Nov 20, 2021 | Del Mar | 3UP R D | 3U | | 9.0 | Main | 3 |
| Chilukki Stakes | Nov 20, 2021 | Churchill Downs | 3UP F/M RD | 3U | f | 8.0 | Main | 3 |
| Red Carpet Handicap | Nov 25, 2021 | Del Mar | 3UP F/M RT | 3U | f | 11.0 | T | 3 |
| Comely Stakes | Nov 26, 2021 | Aqueduct | 3YO F R D | 3 | f | 9.0 | Main | 3 |
| Long Island Stakes | Nov 27, 2021 | Aqueduct | 3UP F/M RT | 3U | f | 12.0 | T | 3 |
| Jimmy Durante Stakes | Nov 27, 2021 | Del Mar | 2YO F | 2 | f | 8.0 | T | 3 |
| Berkeley Handicap | Nov 27, 2021 | Golden Gate Fields | 3UP R D | 3U | | 8.5 | AWT | 3 |
| Fall Highweight Handicap | Nov 28, 2021 | Aqueduct | 3UP SPR | 3U | | 6.0 | Main | 3 |
| Cecil B Demille Stakes | Nov 28, 2021 | Del Mar | 2YO | 2 | | 8.0 | T | 3 |
| Go For Wand Handicap | Dec 4, 2021 | Aqueduct | 3UP F/M RD | 3U | f | 8.0 | Main | 3 |
| Mr Prospector Stakes | Dec 11, 2021 | Gulfstream Park | 3UP SPR | 3U | | 7.0 | Main | 3 |
| Sugar Swirl Stakes | Dec 18, 2021 | Gulfstream Park | 3UP F/M SPR | 3U | f | 6.0 | Main | 3 |
| Harlans Holiday Stakes | Dec 18, 2021 | Gulfstream Park | 3UP R D | 3U | | 8.5 | Main | 3 |
| Robert J Frankel Stakes | Dec 31, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 9.0 | T | 3 |
| Sunland Park Derby | Not Run | Sunland Park | 3YO R D | 3 | | 9.0 | Main | 3 |
| Desert Stormer Stakes | Not Run | Santa Anita | 3UP F/M SPR | 3U | f | 6.0 | Main | 3 |
| Super Derby | Not Run | Louisiana Downs | 3YO R D | 3 | | 8.5 | Main | 3 |
| Cardinal Stakes | Not Run | Churchill Downs | 3UP F/M RT | 3U | f | 9.0 | T | 3 |
| River City Handicap | Not Run | Churchill Downs | 3UP R T | 3U | | 9.0 | T | 3 |
| Commonwealth Turf Stakes | Not Run | Churchill Downs | 3YO R T | 3 | | 8.5 | T | 3 |