| Joe Hernandez Stakes | Jan 1, 2021 | Santa Anita | 3UP T SPR | 3U | | 6.5 | T | 2 |
| San Gabriel Stakes | Jan 2, 2021 | Santa Anita | 3UP R T | 3U | | 9.0 | T | 2 |
| Santa Ynez Stakes | Jan 3, 2021 | Santa Anita | 3YO F SPR | 3 | f | 7.0 | Main | 2 |
| Inside Information Stakes | Jan 23, 2021 | Gulfstream Park | 3UP F/M SPR | 3U | f | 7.0 | Main | 2 |
| San Pasqual Stakes | Jan 30, 2021 | Santa Anita | 3UP R D | 3U | | 9.0 | Main | 2 |
| San Marcos Stakes | Feb 6, 2021 | Santa Anita | 3UP R T | 3U | | 10.0 | T | 2 |
| San Vicente Stakes | Feb 6, 2021 | Santa Anita | 3YO SPR | 3 | | 7.0 | Main | 2 |
| Rachel Alexandra Stakes | Feb 13, 2021 | Fair Grounds | 3YO F R D | 3 | f | 8.5 | Main | 2 |
| Risen Star Stakes | Feb 13, 2021 | Fair Grounds | 3YO R D | 3 | | 9.0 | Main | 2 |
| Santa Monica Stakes | Feb 13, 2021 | Santa Anita | 3UP F/M SPR | 3U | f | 7.0 | Main | 2 |
| Buena Vista Stakes | Feb 20, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 8.0 | T | 2 |
| Winstar Gulfstream Park Mile Stakes | Feb 27, 2021 | Gulfstream Park | 3UP R D | 3U | | 8.0 | Main | 2 |
| Mac Diarmida Stakes | Feb 27, 2021 | Gulfstream Park | 3UP R T | 3U | | 11.0 | T | 2 |
| Davona Dale Stakes | Feb 27, 2021 | Gulfstream Park | 3YO F R D | 3 | f | 8.0 | Main | 2 |
| Fountain Of Youth Stakes | Feb 27, 2021 | Gulfstream Park | 3YO R D | 3 | | 8.5 | Main | 2 |
| San Carlos Stakes | Mar 6, 2021 | Santa Anita | 3UP SPR | 3U | | 7.0 | Main | 2 |
| San Felipe Stakes | Mar 6, 2021 | Santa Anita | 3YO R D | 3 | | 8.5 | Main | 2 |
| Hillsborough Stakes | Mar 6, 2021 | Tampa Bay Downs | 3UP F/M RT | 3U | f | 9.0 | T | 2 |
| Tampa Bay Derby | Mar 6, 2021 | Tampa Bay Downs | 3YO R D | 3 | | 8.5 | Main | 2 |
| Azeri Stakes | Mar 13, 2021 | Oaklawn Park | 3UP F/M RD | 3U | f | 8.5 | Main | 2 |
| Rebel Stakes | Mar 13, 2021 | Oaklawn Park | 3YO R D | 3 | | 8.5 | Main | 2 |
| New Orleans Classic Stakes | Mar 20, 2021 | Fair Grounds | 3UP R D | 3U | | 9.0 | Main | 2 |
| Muniz Memorial Classic Stakes | Mar 20, 2021 | Fair Grounds | 3UP R T | 3U | | 9.0 | T | 2 |
| Fair Grounds Oaks | Mar 20, 2021 | Fair Grounds | 3YO F R D | 3 | f | 8.5 | Main | 2 |
| Louisiana Derby | Mar 20, 2021 | Fair Grounds | 3YO R D | 3 | | 9.5 | Main | 2 |
| Pan American Stakes | Mar 27, 2021 | Gulfstream Park | 3UP R T | 3U | | 12.0 | T | 2 |
| Gulfstream Park Oaks | Mar 27, 2021 | Gulfstream Park | 3YO F R D | 3 | f | 8.5 | Main | 2 |
| Wood Memorial Stakes | Apr 3, 2021 | Aqueduct | 3YO R D | 3 | | 9.0 | Main | 2 |
| Royal Heroine Stakes | Apr 3, 2021 | Santa Anita | 3UP F/M RT | 3U | f | 8.0 | T | 2 |
| Santa Anita Oaks | Apr 3, 2021 | Santa Anita | 3YO F R D | 3 | f | 8.5 | Main | 2 |
| Shakertown Stakes | Apr 3, 2021 | Keeneland | 3UP T SPR | 3U | | 5.5 | T | 2 |
| Appalachian Stakes | Apr 3, 2021 | Keeneland | 3YO F R T | 3 | f | 8.0 | T | 2 |
| Blue Grass Stakes | Apr 3, 2021 | Keeneland | 3YO R D | 3 | | 9.0 | Main | 2 |
| Oaklawn Handicap | Apr 17, 2021 | Oaklawn Park | 3UP R D | 3U | | 9.0 | Main | 2 |
| Californian Stakes | Apr 17, 2021 | Santa Anita | 3UP R D | 3U | | 9.0 | Main | 2 |
| Elkhorn Stakes | Apr 17, 2021 | Keeneland | 3UP R T | 3U | | 12.0 | T | 2 |
| Santa Margarita Stakes | Apr 24, 2021 | Santa Anita | 3UP F/M RD | 3U | f | 9.0 | Main | 2 |
| Alysheba Stakes | Apr 30, 2021 | Churchill Downs | 3UP R D | 3U | | 8.5 | Main | 2 |
| Turf Sprint Stakes | Apr 30, 2021 | Churchill Downs | 3UP T SPR | 3U | | 5.5 | T | 2 |
| Edgewood Stakes | Apr 30, 2021 | Churchill Downs | 3YO F R T | 3 | f | 8.5 | T | 2 |
| Eight Belles Stakes | Apr 30, 2021 | Churchill Downs | 3YO F SPR | 3 | f | 7.0 | Main | 2 |
| Churchill Distaff Turf Mile Stakes | May 1, 2021 | Churchill Downs | 3UP F/M RT | 3U | f | 8.0 | T | 2 |
| Pat Day Mile Stakes | May 1, 2021 | Churchill Downs | 3YO R D | 3 | | 8.0 | Main | 2 |
| American Turf Stakes | May 1, 2021 | Churchill Downs | 3YO R T | 3 | | 8.5 | T | 2 |
| Sheepshead Bay Stakes | May 1, 2021 | Belmont Park | 3UP F/M RT | 3U | f | 11.0 | T | 2 |
| Fort Marcy Stakes | May 1, 2021 | Belmont Park | 3UP R T | 3U | | 9.0 | T | 2 |
| Ruffian Stakes | May 2, 2021 | Belmont Park | 3UP F/M RD | 3U | f | 8.0 | Main | 2 |
| Santa Maria Stakes | May 22, 2021 | Santa Anita | 3UP F/M RD | 3U | f | 8.5 | Main | 2 |
| Charles Whittingham Stakes | May 29, 2021 | Santa Anita | 3UP R T | 3U | | 10.0 | T | 2 |
| Triple Bend Stakes | May 29, 2021 | Santa Anita | 3UP SPR | 3U | | 7.0 | Main | 2 |
| Pennine Ridge Stakes | May 29, 2021 | Belmont Park | 3YO R T | 3 | | 9.0 | T | 2 |
| Summertime Oaks | May 30, 2021 | Santa Anita | 3YO F R D | 3 | f | 8.5 | Main | 2 |
| New York Stakes | Jun 4, 2021 | Belmont Park | 3UP F/M RT | 3U | f | 10.0 | T | 2 |
| Belmont Gold Cup Stakes | Jun 4, 2021 | Belmont Park | 3UP R T | 3U | | 16.0 | T | 2 |
| True North Stakes | Jun 4, 2021 | Belmont Park | 3UP SPR | 3U | | 6.5 | Main | 2 |
| Monrovia Stakes | Jun 5, 2021 | Santa Anita | 3UP T SPR | 3U | f | 6.5 | T | 2 |
| Brooklyn Stakes | Jun 5, 2021 | Belmont Park | 3UP R D | 3U | | 12.0 | Main | 2 |
| Mother Goose Stakes | Jun 26, 2021 | Belmont Park | 3YO F R D | 3 | f | 8.5 | Main | 2 |
| Suburban Stakes | Jul 3, 2021 | Belmont Park | 3UP R D | 3U | | 10.0 | Main | 2 |
| John A Nerud Stakes | Jul 4, 2021 | Belmont Park | 3UP SPR | 3U | | 7.0 | Main | 2 |
| Delaware Handicap | Jul 10, 2021 | Delaware Park | 3UP F/M RD | 3U | f | 10.0 | Main | 2 |
| San Diego Handicap | Jul 17, 2021 | Del Mar | 3UP R D | 3U | | 8.5 | Main | 2 |
| Eddie Read Stakes | Jul 24, 2021 | Del Mar | 3UP R T | 3U | | 9.0 | T | 2 |
| San Clemente Stakes | Jul 24, 2021 | Del Mar | 3YO F R T | 3 | f | 8.0 | T | 2 |
| Honorable Miss Handicap | Jul 28, 2021 | Saratoga | 3UP F/M SPR | 3U | f | 6.0 | Main | 2 |
| Bowling Green Stakes | Jul 31, 2021 | Saratoga | 3UP R T | 3U | | 11.0 | T | 2 |
| Jim Dandy Stakes | Jul 31, 2021 | Saratoga | 3YO R D | 3 | | 9.0 | Main | 2 |
| Amsterdam Stakes | Aug 1, 2021 | Saratoga | 3YO SPR | 3 | | 6.5 | Main | 2 |
| National Museum Of Racing Hall Of Fame Stakes | Aug 6, 2021 | Saratoga | 3YO R T | 3 | | 8.0 | T | 2 |
| Sorrento Stakes | Aug 6, 2021 | Del Mar | 2YO F | 2 | f | 6.0 | Main | 2 |
| Glens Falls Stakes | Aug 7, 2021 | Saratoga | 3UP F/M RT | 3U | f | 12.0 | T | 2 |
| Best Pal Stakes | Aug 7, 2021 | Del Mar | 2YO | 2 | | 6.0 | Main | 2 |
| Yellow Ribbon Handicap | Aug 7, 2021 | Del Mar | 3UP F/M RT | 3U | f | 8.5 | T | 2 |
| Adirondack Stakes | Aug 8, 2021 | Saratoga | 2YO F | 2 | f | 6.5 | Main | 2 |
| Saratoga Special Stakes | Aug 14, 2021 | Saratoga | 2YO | 2 | | 6.5 | Main | 2 |
| Lake Placid Stakes | Aug 21, 2021 | Saratoga | 3YO F R T | 3 | f | 8.5 | T | 2 |
| Del Mar Mile Handicap | Aug 21, 2021 | Del Mar | 3UP R T | 3U | | 8.0 | T | 2 |
| Del Mar Handicap | Aug 21, 2021 | Del Mar | 3UP R T | 3U | | 11.0 | T | 2 |
| Charles Town Classic Stakes | Aug 27, 2021 | Charles Town | 3UP R D | 3U | | 9.0 | Main | 2 |
| Ballston Spa Stakes | Aug 28, 2021 | Saratoga | 3UP F/M RT | 3U | f | 8.5 | T | 2 |
| Pat Obrien Stakes | Aug 28, 2021 | Del Mar | 3UP SPR | 3U | | 7.0 | Main | 2 |
| Prioress Stakes | Sep 4, 2021 | Saratoga | 3YO F SPR | 3 | f | 6.0 | Main | 2 |
| John C Mabee Stakes | Sep 4, 2021 | Del Mar | 3UP F/M RT | 3U | f | 9.0 | T | 2 |
| Del Mar Derby | Sep 4, 2021 | Del Mar | 3YO R T | 3 | | 9.0 | T | 2 |
| Bernard Baruch Handicap | Sep 6, 2021 | Saratoga | 3UP R T | 3U | | 8.5 | T | 2 |
| Remsen Stakes | TBD | Aqueduct | 2YO | 2 | | 9.0 | Main | 2 |
| Demoiselle Stakes | TBD | Aqueduct | 2YO F | 2 | f | 9.0 | Main | 2 |
| Red Smith Stakes | TBD | Aqueduct | 3UP R T | 3U | | 11.0 | T | 2 |
| Pilgrim Stakes | TBD | Belmont Park | 2YO | 2 | | 8.5 | T | 2 |
| Miss Grillo Stakes | TBD | Belmont Park | 2YO F | 2 | f | 8.5 | T | 2 |
| Beldame Stakes | TBD | Belmont Park | 3UP F/M RD | 3U | f | 9.0 | Main | 2 |
| Gallant Bloom Handicap | TBD | Belmont Park | 3UP F/M SPR | 3U | f | 6.5 | Main | 2 |
| Kelso Handicap | TBD | Belmont Park | 3UP R D | 3U | | 8.0 | Main | 2 |
| Vosburgh Stakes | TBD | Belmont Park | 3UP SPR | 3U | | 6.0 | Main | 2 |
| Sands Point Stakes | TBD | Belmont Park | 3YO F R T | 3 | f | 8.0 | T | 2 |
| Hill Prince Stakes | TBD | Belmont Park | 3YO R T | 3 | | 8.0 | T | 2 |
| Kentucky Jockey Club Stakes | TBD | Churchill Downs | 2YO | 2 | | 8.5 | Main | 2 |
| Golden Rod Stakes | TBD | Churchill Downs | 2YO F | 2 | f | 8.5 | Main | 2 |
| Fleur De Lis Stakes | TBD | Churchill Downs | 3UP F/M RD | 3U | f | 9.0 | Main | 2 |
| Falls City Handicap | TBD | Churchill Downs | 3UP F/M RD | 3U | f | 9.0 | Main | 2 |
| Stephen Foster Stakes | TBD | Churchill Downs | 3UP R D | 3U | | 9.0 | Main | 2 |
| Wise Dan Stakes | TBD | Churchill Downs | 3UP R T | 3U | | 8.5 | T | 2 |
| Mrstakes Revere Stakes | TBD | Churchill Downs | 3YO F R T | 3 | f | 8.5 | T | 2 |
| Breeders Cup Juvenile Turf Sprint | TBD | Del Mar | 2YO | 2 | | 5.0 | T | 2 |
| Thoroughbred Aftercare Alliance Stakes | TBD | Del Mar | 3UP R D | 3U | | 13.0 | Main | 2 |
| Seabiscuit Handicap | TBD | Del Mar | 3UP R T | 3U | | 8.5 | T | 2 |
| Hollywood Turf Cup Stakes | TBD | Del Mar | 3UP R T | 3U | | 12.0 | T | 2 |
| Princess Rooney Stakes | TBD | Gulfstream Park | 3UP F/M SPR | 3U | f | 7.0 | Main | 2 |
| Ft Lauderdale Stakes | TBD | Gulfstream Park | 3UP R T | 3U | | 9.0 | T | 2 |
| Kentucky Turf Cup Stakes | TBD | Kentucky Downs | 3UP R T | 3U | | 12.0 | T | 2 |
| Franklin Simpson Stakes | TBD | Kentucky Downs | 3YO SPR | 3 | | 6.5 | T | 2 |
| Bourbon Stakes | TBD | Keeneland | 2YO | 2 | | 8.5 | T | 2 |
| Jessamine Stakes | TBD | Keeneland | 2YO F | 2 | f | 8.5 | T | 2 |
| Thoroughbred Club Of America Stakes | TBD | Keeneland | 3UP F/M SPR | 3U | f | 6.0 | Main | 2 |
| Hagyard Fayette Stakes | TBD | Keeneland | 3UP R D | 3U | | 9.0 | Main | 2 |
| Phoenix Stakes | TBD | Keeneland | 3UP SPR | 3U | | 6.0 | Main | 2 |
| Woodford Stakes | TBD | Keeneland | 3UP T SPR | 3U | | 5.5 | T | 2 |
| Raven Run Stakes | TBD | Keeneland | 3YO F SPR | 3 | f | 7.0 | Main | 2 |
| Los Alamitos Futurity | TBD | Los Alamitos | 2YO | 2 | | 8.5 | Main | 2 |
| Great Lady M Stakes | TBD | Los Alamitos | 3UP F/M SPR | 3U | f | 6.5 | Main | 2 |
| Penn Mile Stakes | TBD | Penn National | 3YO R T | 3 | | 8.0 | T | 2 |
| Presque Isle Downs Masters Stakes | TBD | Prestique Isle | 3UP F/M SPR | 3U | f | 6.5 | AWT | 2 |
| Dinner Party Stakes | TBD | Pimlico | 3UP R T | 3U | | 8.5 | T | 2 |
| Black Eyed Susan Stakes | TBD | Pimlico | 3YO F R D | 3 | f | 9.0 | Main | 2 |
| Gallant Bob Stakes | TBD | Parx Racing | 3YO SPR | 3 | | 6.0 | Main | 2 |
| Chandelier Stakes | TBD | Santa Anita | 2YO F | 2 | f | 8.5 | Main | 2 |
| Zenyatta Stakes | TBD | Santa Anita | 3UP F/M RD | 3U | f | 8.5 | Main | 2 |
| Goldikova Stakes | TBD | Santa Anita | 3UP F/M RT | 3U | f | 8.0 | T | 2 |
| San Antonio Stakes | TBD | Santa Anita | 3UP R D | 3U | | 8.5 | Main | 2 |
| City Of Hope Mile Stakes | TBD | Santa Anita | 3UP R T | 3U | | 8.0 | T | 2 |
| John Henry Turf Championship Stakes | TBD | Santa Anita | 3UP R T | 3U | | 10.0 | T | 2 |
| Santa Anita Sprint Championship Stakes | TBD | Santa Anita | 3UP SPR | 3U | | 6.0 | Main | 2 |
| Eddie D Stakes | TBD | Santa Anita | 3UP T SPR | 3U | | 6.5 | T | 2 |
| Twilight Derby | TBD | Santa Anita | 3YO R T | 3 | | 9.0 | T | 2 |
| Mathis Brothers Mile Stakes | TBD | Santa Anita | 3YO R T | 3 | | 8.0 | T | 2 |